In the group switched from Dang Gui Shao Yao San, a tendency towards increase in plasma estradiol level was observed (1.51-fold, p = 0.055), which was significant compared with that in the group switched from Gui Zhi Fu Ling Wan (p = 0.032). After the 8-week treatment with Wen-jing-tang, plasma LH levels were decreased by 58.2% (p 0.0001) and 49.4% (p = 0.0005) in the groups switched from Dang Gui Shao Yao San and Gui Zhi Fu Ling Wan, respectively. No decrease in mean plasma LH level was observed in the 54 women who failed to ovulate among the 64 treated with a Kampo preparation. Plasma FSH, LH and estradiol levels were measured and ovulation rates were determined at the beginning and after an 8-week treatment with the preceding Kampo prescription, as well as after the subsequent 8-week treatment with the same preparation or Wen-jing-tang. Sixty-four anovulatory women diagnosed with PCOS were enrolled in the study.Īfter Kampo diagnosis, subjects received matched Kampo preparations (43 cases: Dang-gui-shao-yao-san, 21 cases: Gui Zhi Fu Ling Wan) selected by the matching theory of eight-principle pattern identification and Kampo diagnosis based on concepts of the qi, blood, and fluids as the physiologic activity.įifty-four women who failed to ovulate after an 8-week treatment were randomly allocated to continuation of treatment with the preceding Kampo prescription (continuation group, n = 27) or treatment with Wen Jing Tang (switching group, n = 27). The objective of this study was to investigate the effects of switching therapy to Wen-jing-tang (Unkei-to) from previous selected herbal preparations on endocrine levels and induction of ovulation in women with polycystic ovary syndrome ( PCOS). ![]() ![]() After 4 years of trying to conceive, I had a total sum of 6 weeks treatment before falling pregnant The Chinese herbal formula wen jing tang improves PCOS in women
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